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<h1 class="pagehead">Scientific Presentations</h1>
<h2> </h2>
<h2><strong>2012 </strong></h2>
<h3><strong>Society of Nuclear Medicine 2012 Annual Meeting</strong></h3>
<p>Armor TW<sup>1</sup>, Haberkorn U<sup>2</sup>, Zechmann C<sup>2</sup>, Babich JW.<sup>1</sup> <em>A Comparison of 2D and 3D Regions within the Same Patient to Derive Organ and Tissue Kinetics.</em><br />
Abstract # 13, June 10, 2012<br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; <sup>2</sup>Nuclear Medicine, University of Heidelberg, Heidelberg, Germany<br />
<a href="../downloads/Abstract_13.pdf">View Abstract</a> </p>
<p>Hillier SM<sup>1</sup>, Rubino K<sup>1</sup>, Maresca KP<sup>1</sup>, Marquis JC<sup>1</sup>, Tesson M<sup>2</sup>, Zimmerman CN<sup>1</sup>, Eckelman WC<sup>1</sup>, Mairs R<sup>2</sup>, Joyal JL<sup>1</sup>, Babich JW<sup>1</sup>. <em>[131I]MIP-1466, A Small Molecule Prostate-Specific Membrane Antigen (PSMA) Inhibitor for Targeted Radiotherapy of Prostate Cancer (PCa).</em><strong> </strong><br />
Abstract # 170, June 11, 2012<br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA;<sup>2</sup>University of Glasgow, Glasgow, UK<br />
<a href="../downloads/Abstract_170.pdf">View Abstract</a></p>
<p>Babich JW<sup>1</sup>, Coleman ER<sup>2</sup>, Van Heertum R<sup>3</sup>, Vallabhajosula S<sup>4</sup>, Goldsmith SJ<sup>4</sup>, Osborne J<sup>4</sup>, Slawin K<sup>5</sup>, Joyal JL<sup>1</sup>. <em>Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA) for SPECT: Summary of Phase I Studies in Patients with Prostate Cancer (PCa).</em><br />
Abstract # 179, June 11, 2012<br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; <sup>2</sup>Duke Medical Center, Durham, NC; <sup>3</sup>New York Presbyterian Hospital, New York, NY; <sup>4</sup>Weill Cornell, New York, NY; <sup>5</sup>Vanguard Urologic Institute, Houston, TX<br />
<a href="../downloads/Abstract_179.pdf">View Abstract</a> </p>
<p>Maresca KP, Wang JC, Hillier SM, Femia FJ, Lu G, Zimmerman CN, Kronauge JF, Eckelman WC, Joyal JL, Babich JW. <em>Development of a Simple Kit for Tc-99m-MIP-1404, a Single Amino Acid Chelate (SAAC II) Derived Small Molecule Inhibitor of Prostate Specific Membrane Antigen (PSMA) for Imaging Prostate Cancer.</em><br />
Abstract # 523, June 13, 2012<br />
Molecular Insight Pharmaceuticals, Inc., Cambridge, MA<br />
<a href="../downloads/Abstract_523.pdf">View Abstract</a> </p>
<p>Maresca KP, Wang JC, Hillier SM, Marquis JC, Zimmerman CN, Kronauge JF, Eckelman WC, Joyal JL, Babich JW. <em>Radioimpurity Profile of Tc-99m-MIP-1404, a Single Amino Acid Chelate Derived Inhibitor of Prostate Specific Membrane Antigen (PSMA) for Imaging Prostate Cancer.</em><strong> </strong> <br />
Abstract # 1562, June 10, 2012<br />
Molecular Insight Pharmaceuticals, Inc., Cambridge, MA<br />
<a href="../downloads/Abstract_1562.pdf">View Abstract</a></p>
<p>Kothari PJ<sup>1</sup>, Vallabhajosula S<sup>1</sup>, Schoendorf M<sup>1</sup>, Lu G<sup>2</sup>, Zimmerman CN<sup>2</sup>, Hillier SM<sup>2</sup>, <nobr>Maresca KP<sup>2</sup>,</nobr> Eckelman WC<sup>2</sup>, Joyal JL<sup>2</sup>, Babich JW<sup>2</sup>. <em>18F-labeled Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA) for PET Imaging of Prostate Cancer.</em><strong> </strong> <br />
Abstract # 1721, June 10, 2012<br />
<sup>1</sup>Radiology and Citigroup Biomedical Imaging Center, Weill Cornell Medical College of <nobr>Cornell University,</nobr> New York, NY; <sup>2</sup>Discovery Research, Molecular Insight Pharmaceuticals, Inc., Cambridge, MA<br />
<a href="../downloads/Abstract_1721.pdf">View Abstract</a></p>
<p>Nikolopoulou A<sup>1</sup>, Maresca KP<sup>2</sup>, Vallabhajosula S<sup>1</sup>, Babich JW<sup>2</sup>.<em> <sup>99m</sup>Tc-MIP-1404 for Prostate Cancer Imaging: Validation of a Solid Phase Extraction (SPE) Method to Determine the Radiochemical Purity and Comparison with HPLC Analysis.</em><br />
Abstract # 1757, June 10, 2012<br />
<sup>1</sup>Radiology, Weill Cornell Medical College of Cornell University, New York, NY; <sup>2</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA<br />
<a href="../downloads/Abstract_1757.pdf">View Abstract</a><strong></strong></p>
<h3><strong>ASCO-2012 Genitourinary Cancers Symposium </strong> </h3>
<p>Osborne JR<sup>1</sup>, Hassan N<sup>1</sup>, Vallabhajosula S<sup>1</sup>, Nikolopoulou A<sup>1</sup>, Maresca KP<sup>2</sup>, Hillier SM<sup>2</sup>, Joyal JL<sup>2</sup>, Crummet R<sup>2</sup>, Armor TW<sup>2</sup>, Tagawa S<sup>1</sup>, Goldsmith SJ<sup>1</sup>, Babich JW<sup>2</sup>. <em>Tc-99m Labeled Small Molecular Inhibitors of Prostate Specific Membrane Antigen (PSMA): New Molecular Imaging Probes to Detect Metastatic Prostate Adenocarcinoma (PCa). </em><br />
February 3, 2012 <br />
<sup>1</sup>New York Weill Cornell Medical Center, New York, NY; <sup>2</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA <br />
<a href="../downloads/ASCO2012_GenitourinaryCancersSymposium.pdf">View Abstract </a></p>
<h2><strong>2011 </strong></h2>
<h3><strong>Annual Congress of the European Association of Nuclear Medicine</strong> </h3>
<p>Vallabhajosula S<sup>1</sup>, Osborne J<sup>1</sup>, Nikolopoulou A<sup>1</sup>, Maresca KP<sup>2</sup>, Crummet R<sup>2</sup>, Armor TW<sup>2</sup>, Barrett JA<sup>2</sup>, Tagawa S<sup>1</sup>, Goldsmith SJ<sup>1</sup>, Babich JW<sup>2</sup>. <em>Novel <sup>99m</sup>Tc-labeled Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA): Initial Experience in Healthy Volunteers and Men with Metastatic Prostate Adenocarcinoma (PCa).</em> <br />
October 18, 2011 <br />
<sup>1</sup>Weill Cornell Medical College, Cornell University New York Presbyterian Hospital, New York, NY; <sup>2</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA <br />
<a href="../downloads/EANM2011_Abstract.pdf">View Abstract</a><br />
<a href="../downloads/EANM2011_Presentation.pdf">View Presentation</a></p>
<h3><strong>Society of Nuclear Medicine 2011 Annual Meeting</strong></h3>
<p>Hillier SM<sup>1</sup>, Merkin R<sup>1</sup>, Maresca, KP<sup>1</sup>, Zimmerman CN<sup>1</sup>, Barrett JA<sup>1</sup>, Tesson M<sup>2</sup>, Eckelman WC<sup>1</sup>, Mairs R<sup>2</sup>, Joyal JL<sup>1</sup>, Babich JW<sup>1</sup>. <em><sup>131</sup>I MIP-1375, A Small Molecule Prostate-Specific Membrane Antigen (PSMA) Inhibitor for Targeted Therapy of Prostate Cancer (PCa).</em><br />
Abstract #361, June 7, 2011<br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; <sup>2</sup>Centre of Oncology and Applied Pharmacology, University of Glasgow, Glasgow, Scotland, UK<br />
<a href="../downloads/SNM2011_Abstract_361.pdf">View Presentation</a></p>
<h2><strong>2010</strong></h2>
<h3><strong>ASCO-European Organization for Research and Treatment of Cancer, NATIONAL CANCER INSTITUTE</strong></h3>
<p>Joyal JL, Hillier SM, Kern AM, Maresca KP, Marquis JC, Femia FJ, Zimmerman CN, Barrett JA, Eckelman WC, Babich JW. <em>Monitoring Prostate Cancer Response to Paclitaxel by Molecular Imaging of PSMA</em><br />
October 18, 2010<br />
Molecular Insight Pharmaceuticals, Inc., Cambridge, MA <br />
<a href="../downloads/ASCO_EORTC_NCI2010_PaxPoster.pdf">View Abstract</a></p>
<h3><strong>Annual Congress of the European Association of Nuclear Medicine </strong></h3>
<p>Barrett JA<sup>1</sup>, LaFrance ND<sup>1</sup>, Armor TW<sup>1</sup>, Goldsmith SJ<sup>2</sup>, Vallabhajosula S<sup>2</sup>, Kipper SL<sup>3</sup>, Maresca KP<sup>1</sup>, Femia FJ<sup>1</sup>, Stubbs JB<sup>3</sup>, Stabin MG<sup>3</sup>, Joyal JL<sup>1</sup>, Babich JW<sup>1</sup>. <em>Detection of Metastatic Prostate Cancer (PCa) in Soft Tissue, Bone, and Prostate with <sup>123</sup>I-MIP-1072: A Comparison with <sup>111</sup>In-Capromab Pendetide.<br />
</em>Abstract #OP334, October 11, 2010 <br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; <sup>2</sup>Weill Medical College of Cornell University; <sup>3</sup>Radiation Dosimetry Services, Inc. <br />
<a href="../downloads/EANM2010_Abstract_0P334.pdf">View Presentation</a> </p>
<p>Hillier SM<sup>1</sup>, Maresca KP<sup>1</sup>, Merkin RD<sup>1</sup>, Tesson M<sup>2</sup>, Barrett, JA<sup>1</sup>, Mairs R<sup>2</sup>, Eckelman WC<sup>3</sup>, <nobr>Joyal JL<sup>1</sup>,</nobr> Babich JW<sup>1</sup>. <em>Inhibition of Human Prostate Cancer Growth by Targeting Prostate Specific Membrane Antigen (PSMA) Using an I-131 Labeled Small Molecule Inhibitor. </em><br />
Abstract #OP552, October 13, 2010<br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; <sup>2</sup>University of Glasgow; <sup>3</sup>Molecular Tracers, LLC<br />
<a href="../downloads/EANM2010_Abstract_1608.pdf">View Presentation</a></p>
<h3><strong>Society of Nuclear Medicine 2010 Annual Meeting</strong></h3>
<p>Hillier SM, Kern AM, Maresca KP, Marquis JC, Femia FJ, Zimmerman CN, Eckelman WC, Joyal JL, Babich JW. <em>Molecular Imaging for Monitoring Prostate Cancer Response to Paclitaxel</em><br />
Abstract #14, June 6, 2010<br />
<a href="../downloads/SNM2010_Abstract_14.pdf">View Presentation</a> </p>
<p>Maresca KP, Hillier SM, Lu G, Marquis JC, Zimmerman CN, Eckelman WC, Joyal, JL, Babich, JW. <em>Influence of Functionalized Chelators on Affinity and Pharmacokinetics of <sup>99m</sup>Tc(CO)<sub>3</sub>-Labeled Small Molecules Targeting Prostate Specific Membrane Antigen (PSMA). </em><br />
Abstract #250, June 7, 2010<br />
<a href="../downloads/SNM2010_Abstract_250.pdf">View Presentation</a> </p>
<p>Hillier SM<sup>1</sup>, Maresca KP<sup>1</sup>, Lu G<sup>1</sup>, Marquis JC<sup>1</sup>, Zimmerman CN<sup>1</sup>, Nimmagadda S<sup>2</sup>, Eckelman WC<sup>1</sup>, Pomper MG<sup>2</sup>, Joyal JL<sup>1</sup>, Babich JW<sup>1</sup>. <em><sup>99m</sup>Tc-MIP-1340, a Small Molecule Inhibitor of PSMA for Molecular Imaging of Prostate Cancer.</em> <br />
Abstract #481, June 8, 2010 <br />
<sup>1</sup>Molecular Insight Pharmaceuticals, Inc., Cambridge, MA, <sup>2</sup>Johns Hopkins Medical Institute, Baltimore, MD<br />
<a href="../downloads/SNM2010_Abstract_481.pdf">View Presentation</a></p>
<h2><strong>2009 </strong> </h2>
<h3><strong>Society of Nuclear</strong> <strong>Medicine 2009 Annual Meeting</strong></h3>
<p>Barrett JA, LaFrance, ND, Coleman RE, Goldsmith SJ, Stubbs JB, Petry N, Vallabhajosula S, Maresca KP, Femia FJ, Stabin MG, Babich JW. <em>Targeting Metastatic Prostate Cancer (PCa) in Patients Using 123I-MIP 1072 & 123I-MIP 1095.</em> <br />
Abstract #522, June 16, 2009 </p>
<p>Maresca KP, Hillier SM, Lu G, Marquis JC, Zimmerman CN, Eckelman WC, Joyal JL, Babich JW. <br />
<em>Molecular Targeting Using Advanced Single Amino Acid Chelates (SAAC) for 99mTc.</em> <br />
Abstract #146, June 15, 2009 </p>
<h3>Third International Symposium on Cancer Metastasis and Lymphovascular System: Basis for Rational Therapy</h3>
<p>Joyal JL. <em>Novel Small Molecules for Imaging Soft Tissue and Bone Metastasis in Prostate Cancer.</em><em><br />
</em>May 7, 2009
</p>
<h2><strong>2008</strong> </h2>
<h3><strong>Society of Nuclear Medicine 2008 Annual Meeting</strong></h3>
<p>Hillier SM, Maresca KP, Femia FJ, Zimmerman CN, Barrett JA, Foss CA, Eckelman WC, Pomper MG, Joyal JL, Babich JW. <em>Small Molecule PSMA Inhibitors for Targeted Molecular Imaging of Prostate Cancer. </em><br />
Abstract #389, June 17, 2008 </p>
<p>Femia FJ, Maresca KP, Hillier SM, Marquis JC, Luss-Lusis E, Zimmerman CN, Joyal JL, Abeysekera B, Kronauge JF, Babich JW. [<em>123I]MIP-1095 for Targeting Prostate Cancer Via Prostate Specific Membrane Antigen (PSMA): A High Specific Activity Radio-Synthesis. </em><br />
Abstract #393, June 17, 2008</p>
<p>Maresca KP, Hiller SM, Femia FJ, Barone C, Keith D, Joyal JL, Zimmerman CN, Barrett JA, Eckelman WC, Babich JW. <em>The Development of an SAR with Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA).<br />
</em> June 17, 2008 <br />
</p>
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