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   <h2>Neal Mantick Joins Abt Associates as Director of Registries</h2>

<strong>Cambridge, Mass. August 7, 2006</strong> &mdash; Neal S. Mantick, a skilled manager with over 22 years of experience in the pharmaceutical and biotech industries, has joined Abt Associates as Director of Registries.&nbsp; He will provide technical oversight and supervision for all registry projects, including design, implementation, and reporting, and will consult with sponsors to help optimize the receptivity, adoption, and long-term acceptance of new, innovative drug products and medical devices. Mr. Mantick comes to Abt Associates from Genzyme Corporation, where he served as Director of Global Registry Programs.


<p>"There is ever-increasing pressure from a variety of sources &mdash; most significantly the FDA, payors, and patients &mdash; to obtain the kind of intelligence that is more readily available from a post-marketing study than from a clinical trial. This is true of all potential registry objectives, such as defining the natural history / burden of illness, confirming clinical effectiveness, monitoring safety and managing risk, estimating cost effectiveness, and measuring quality of care," said Steve Fosburg, Sr. Vice President of Clinical Research Studies. "We believe that Neal's leadership will further strengthen our strategic design and operational capabilities as we continue to evolve to meet the needs of the industry."</p>

<p>During his eight years at Genzyme, Mr. Mantick was responsible for leading multifunctional teams in the overall definition, design, planning, implementation, and ongoing management of four global registries for rare diseases.&nbsp; In that capacity, he had the opportunity to participate in groundbreaking advancements in the medical treatment of patients with genetic diseases and to lead the registry programs through a time of substantial growth and evolution, meeting a wider range of clinical, regulatory, and commercial expectations.&nbsp; Mr. Mantick's registry expertise is built on a strong foundation of product development and clinical studies management experience gained during his affiliation with The Upjohn Company, Arthur D. Little, and PAREXEL International.</p>

<p>"Abt Associates is in a truly exciting position to blend its expertise in registries, clinical operations, biostatistics and epidemiology, health economics and quality of life research, and healthcare market research to provide comprehensive and innovative solutions in collaboration with our clients in a progressively more complex healthcare delivery environment," said Mr. Mantick. "I am looking forward to contributing to the development of Abt Associates's staffing and process infrastructure as part of a strong foundation for an expanding U.S. and European registries service."</p>

<p>Mr. Mantick holds a B.S. degree in Pharmacy from the University of Kentucky and an M.S. degree in Health Policy and Management from the Harvard University School of Public Health.&nbsp; He is a contributing author to "Registries for Evaluating Patient Outcomes" (under development), sponsored by the Agency for Healthcare Research and Quality, and has previously been a featured speaker at conferences sponsored by the Drug Information Association, American Society of Gene Therapy, and Center for Business Intelligence.</p>

<p>Abt Associates, a private, employee-owned company, applies scientific research and technical assistance expertise to a wide range of social, economic and technological policy issues; international development; clinical trials and registries; and complex business problems.&nbsp; Founded in 1965, Abt Associates provides services to U.S. federal, state and local governments; foreign governments; international organizations; foundations; and business and industry.&nbsp; Its staff of over 1,000 is located in Cambridge, Massachusetts; Bethesda, Maryland; Chicago, Illinois; and in Africa, Asia, Central Asia, Europe, Latin America and the Middle East.</p>


<h3>Contact</h3>

<p>Julia Altman<br />
  Director of Marketing<br />
  781.372.6658<br />
  <a href="mailto: [email protected]">[email protected]</a></p>
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