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<h1>Ophthalmology</h1>
<p>The ABS team has extensive experience conducting various strategic and tactical, prospective and retrospective research and consulting services in ophthalmology. Examples of this work are presented here.</p>
<h2>Indications</h2>
<ul>
<li>Age-related macular degeneration (AMD)</li>
<li>Astigmatism</li>
<li>Bacterial conjunctivitis</li>
<li>Cataract</li>
<li>Contact lens</li>
<li>Dry eye syndrome</li>
<li>Glaucoma</li>
<li>Hyperopia</li>
<li>Intraocular lens</li>
<li>Meibomian gland disease</li>
<li>Microbial keratitis</li>
<li>Myopia</li>
<li>Ocular allergy</li>
<li>Ophthalmic surgery</li>
<li>Pediatric eye conditions</li>
<li>Ulcerative keratitis</li>
</ul>
<h2>Strategic Consulting and Research Examples</h2>
<ul>
<li>Concept volume positioning test for new contact lens products</li>
<li>Exploratory consumer focus groups for contact lenses</li>
<li>Focus group evaluation of a disinfection system</li>
<li>Literature review of the clinical, economic and quality of life burden of dry eye syndrome</li>
<li>Market launch, clinical and economic messaging, and pricing strategy for a therapy in AMD</li>
<li>Opaque soft contact lens name evaluation</li>
</ul>
<h2>Selected Prospective Studies</h2>
<ul>
<li>Current cohort study and case-control study of ulcerative keratitis among contact lens wearers</li>
<li>Epidemiology studies examining complications and symptoms associated with disposable extended and daily wear contact lenses compared to conventional soft extended and daily wear contact lenses</li>
<li>Physician survey of clinical and economic outcomes of alternative therapies for cataract patients with astigmatism</li>
<li>Post-approval open label study of microbial keratitis and visual acuity in individuals with extended wear contact lenses</li>
<li>Pre-market approval (PMA) trial of an intraocular lens</li>
</ul>
<h2>Selected Retrospective Studies and Modeling Studies</h2>
<ul>
<li>Cost of illness study of pediatric eye conditions using the Medical Expenditure Panel Survey (MEPS) examining eye and non-eye related services and possible disparities in care</li>
<li>Economic model in AMD</li>
<li>Medicare analyses of the clinical and economic outcomes of care of cataract and other ophthalmologic surgical procedures</li>
<li>Model to assess the economic impact of a blue-filtering intraocular lenses on AMD associated with cataract surgery</li>
<li>Prevalence study of pediatric eye conditions using MEPS</li>
</ul>
<h2>Selected Policy Engagements</h2>
<ul>
<li>Large-scale evaluation project for Medicare of the quality of care, and patient and economic impacts of payment alternatives for providers of cataract surgery</li>
</ul>
<h2>Selected Publications & Presentations of ABS Team Members</h2>
<p>Ganz ML, Xuan Z, Hunter DG. Patterns of eye care use and expenditures among children with diagnosed eye conditions. J AAPOS 2007; 11: 480-7.</p>
<p>Ganz ML, Xuan Z, Hunter DG. Prevalence and correlates of children’s diagnosed eye and vision conditions. Ophthalmology 2006; 113(12): 2298-2306.</p>
<p>Reddy P, Gao X, Barnes R, Fairchild C, Boci K, Waycaster C, Pashos C. The economic impact of blue-light filtering intraocular lenses on age-related macular degeneration associated with cataract surgery: a third-party payer’s perspective. Curr Med Res Opin 2006; 22(7): 1311-8.</p>
<p>Reddy P, Grad O, Rajagopalan K. The economic burden of dry eye: a conceptual framework and preliminary assessment. Cornea 2004; 23: 751-61.</p>
<p>Menzin J, Friedman M, Cavanaugh R, Boulanger L, Lewis B. A randomized clinical trial to assess the outcomes and cost of levocabastine eye drops versus loratadine in the treatment of seasonal allergic rhinoconjunctivitis. Society of General Internal Medicine, 22nd Annual Meeting, San Francisco, CA, April 29 - May 1, 1999.</p>
<p>Street DA, Javitt JC, Wang Q, Tielsch JM, Canner JK, Bass EB, Steinberg EP. Atherosclerotic disease in patients undergoing cataract extraction. A nationwide case control study. The Cataract Patient Outcomes Research Team. Arch Ophthal 1996; 114(11): 1407-11.</p>
<p>Javitt JC, Wang F, McBean AM, Wang Q, Metrick S, Glaser S. The use and costs of physician services for ophthalmic surgical procedures in 1988 and 1991. Ophthalmic Surg Lasers 1996; 27(7): 575-82.</p>
<p>Javitt JC, Street DA, Tielsch JM, Wang Q, Kolb MM, Schien O, Sommer A, Bergner M, Steinberg EP. National outcomes of cataract extraction. Retinal detachment and endophthalmitis after outpatient cataract surgery. Cataract Patient Outcomes Research Team. Ophthalmology 1994; 101(1): 100-5.</p>
<p>Poggio EC, Abelson MB. Complications and symptoms with disposable daily wear contact lenses and conventional soft daily wear contact lenses. CLAO Journal (now Eye & Contact Lens: Science and Clinical Practice) 1993; 19(2): 95-102.</p>
<p>Poggio EC, Abelson M. Complications and symptoms in disposable extended wear lenses compared with conventional soft daily wear and soft extended wear lenses. CLAO Journal (now Eye & Contact Lens: Science and Clinical Practice) 1993; 19(1): 31-9.</p>
<p>Glynn RJ, Schein OD, Seddon JM, et al. The incidence of ulcerative keratitis among aphakic contact lens wearers in New England. Arch Ophthal 1991; 109(1): 104-7.</p>
<p>Schein OD, Poggio EC. Ulcerative keratitis in contact lens wearers. Incidence and risk factors. Cornea 1990; 9 Suppl 1: S55-8.</p>
<p>Schein OD, Glynn RJ, Poggio EC, Seddon JM, Kenyon KR. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. A case-control study. Microbial Keratitis Study Group. NEJM 1989; 321(12): 773-8.</p>
<p>Poggio EC, Glynn RJ, Schein OD, et al. The incidence of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. NEJM 1989; 321(12): 779-83.</p>
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