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<h1>DIAGNOSTICS Research </h1>
<p>The ABS team has extensive experience conducting various strategic and tactical, prospective and retrospective research and consulting services to assess and demonstrate the value of medical diagnostics. Examples of this work are presented here.</p>
<h2>Indications</h2>
<ul>
<li>Blood transfusion</li>
<li>Cancer imaging and screening</li>
<li>Cardiac diagnosis, monitoring, and imaging </li>
<li>Hepatitis B</li>
<li>Rheumatoid arthritis </li>
<li>Urology</li>
</ul>
<h2>Strategic Consulting and Research Examples</h2>
<ul>
<li>AMCP-compliant dossier related to echocardiography</li>
<li>Global market research on consumer applications of cardiovascular and physiologic monitoring technologies </li>
<li>Strategic outcomes research and reimbursement plan for a cardiology diagnostic test</li>
<li>Systematic review of a diagnostic procedure in rheumatoid arthritis</li>
</ul>
<h2>Selected Prospective Studies</h2>
<ul>
<li>Patient registry on longitudinal outcomes of cardiac imaging </li>
<li>Studies of a gastrointestinal and urology endoscope, an MRI breast imaging system, and a thrombosis imaging agent using monoclonal antibodies</li>
</ul>
<h2>Selected Retrospective Studies</h2>
<ul>
<li>Sensitivity and specificity analyses of a drug used during cardiovascular diagnostic procedures and diagnostic assays in newborns</li>
</ul>
<h2>Selected Modeling Studies</h2>
<ul>
<li>Clinical effectiveness model of eight colorectal cancer screening strategies </li>
<li>Cost-effectiveness models of computer-assisted breast cancer screening device using Monte-Carlo simulations, hepatitis B screening among pregnant women, and lipoprotein particle concentration measurement in managing congestive heart disease </li>
<li>Economic models of diagnostic modality in blood transfusion in multiple countries, colorectal cancer, echocardiography, and various contrast media in CT scans</li>
</ul>
<h2>Selected Policy Engagements</h2>
<ul>
<li>Analysis of factors affecting the diffusion of MRI technologies</li>
</ul>
<h2>Selected Publications & Presentations of ABS Team Members</h2>
<p> Lee WC, et al. Timely confirmation of gastro-esophageal reflux disease via pH monitoring: Estimating budget impact on managed care organizations. Curr Med Res Opin 2008; 24(5): 1317-27.</p>
<p> Lee WC, Yeh YC, Atzinger C, Pashos CL. Clinical and economic impact of increased colonoscopy screening in the United States: a computer simulation of a Markov model. Digestive Disease Week (DDW), Washington, DC, May 19-24, 2007.</p>
<p> Straus WL, Mansley EC, Gold KF, Wang Q, Reddy P, Pashos CL. Colorectal cancer screening attitudes and practices in the general population: a risk-adjusted survey. J Public Health Manag Pract 2005; 11(3): 244-51.</p>
<p> Saigal CS, Pashos CL, et al. Variations in use of imaging in a national sample of men with early stage prostate cancer. Urology 2002; 59(3): 400-4.</p>
<p> Straus W, Gold KF, Pashos CL, et al. Barriers to four colorectal cancer screening tests: identification of knowledge, concerns, attitudes and beliefs of persons at risk. Poster of Distinction at DDW, Atlanta, GA, May 20-23, 2001.</p>
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