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<TITLE>EPSIS - Electroconductive Polymer Sensor Interrogation System</TITLE>
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<P ALIGN=left><span class="style2"> <B>EPSIS
(Electroconductive Polymer Sensor Interrogation System</B></span><B><FONT COLOR="#ffffff">)</FONT></B></P>
</TD>
</TR>
</TABLE>
<TABLE WIDTH=650 BORDER=0 CELLPADDING=0 CELLSPACING=0>
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<TD WIDTH=220 VALIGN=TOP>
<P><A HREF="gifs\epsis1l.GIF"><IMG SRC="gifs/epsis1s.gif" NAME="Graphic1" WIDTH=143 HEIGHT=175 BORDER=0 ISMAP></A></P>
<P><FONT FACE="arial"><FONT SIZE=2><B>Model EPSIS 240 II US</B></FONT></FONT></P> </TD>
<TD WIDTH=281>
<P ALIGN=CENTER><a href="gifs\epsis2l.GIF"><img src="gifs/epsis2s.gif" width=228 height=172 border=0></a></P>
<P ALIGN=CENTER><FONT FACE="arial"><FONT SIZE=2><B>Model EPSIS
240 II CS</B></FONT></FONT></P> </TD>
<TD WIDTH=195 VALIGN=TOP>
<P><A HREF="aboutl.gif"><IMG SRC="gifs/abouts.gif" NAME="Graphic3" ALIGN=BOTTOM WIDTH=165 HEIGHT=130 BORDER=0></A></P>
<P ALIGN=CENTER><A HREF="gifs\epsscrn3.gif"><B>EPSISoft
Release 2.0</B></A></P> </TD>
</TR>
</TABLE>
</DL>
<P ALIGN=CENTER><B><I>for </I>B i o s e n s o r A s s a y s</B></P>
<TABLE WIDTH=637 BORDER=0 CELLPADDING=2 CELLSPACING=0>
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<TD WIDTH=146 HEIGHT=26 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="epsis.html#introduction">Introduction
and Background</A></P> </TD>
<TD WIDTH=159 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="epsis.html#applications">Applications
of EPSIS</A></P> </TD>
<TD WIDTH=141 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="epsis.html#specifications">Technical
Specifications</A></P> </TD>
<TD WIDTH=69 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="epsis.html#methods">Principle</A></P> </TD>
<TD WIDTH=73 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="epsis.html#appnotes">Application
Notes</A></P> </TD>
<TD WIDTH=75 class="style1">
<P ALIGN=CENTER class="style1"><A HREF="pricelist-cart.html" target="pricelist">Price
List</A></P> </TD>
</TR>
</TABLE>
<TABLE WIDTH=650 BORDER=0 CELLPADDING=0 CELLSPACING=0>
<COL WIDTH=885>
<TR>
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<P><IMG SRC="tbullet.gif" NAME="Graphic10" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<B>Introduction and Background</B></P>
<BLOCKQUOTE class="style1">
<div align="justify">The EPSIS 240II now
boasts a new hardware configuration for software selectable two
electrode and three electrode modes of sensor interrogation. This
is a key and important development. With the two electrode mode,
the user may now reliably and conveniently interrogate conductive
polymer gas and vapor phase analytes -- useful in the development
of electronic noses and VOC sensors - without resorting to
previous electrode patch-ins. EPSIS continues, in its
three-electrode mode, to offer its innovative electroconductive
polymer sensor interrogation configuration for the development of
conductimetric chemical sensors and biosensors.</div>
</BLOCKQUOTE>
<div align="justify">
<BLOCKQUOTE class="style1">EPSIS is the first
of its kind sensor interrogation system designed specifically for
research and applications-specific product development of
chemical and biological sensors based on electroconductive
polymer sensor technology. EPSIS is based on a patented
analytical method that combines potentiometric, potentiostatic,
and superior pulsed DC chronocoulometric capabilities in one
unit. These electrochemical capabilities are sequentially
combined to provide a powerful and versatile detection and
measurement scheme that is unique to electroconductive polymer
transducers. The result is a conductimetric response that
detects, measures, and reports changes in electrical conductivity
as electroconductive transducers respond to specific analytes to
which they have been rendered chemically or biologically
specific.</BLOCKQUOTE>
</div>
<P ALIGN=justify class="style1"><A HREF="epsis.html#top">Back
to Index</A></P>
<HR align="JUSTIFY">
<H3 ALIGN=justify class="style1"><IMG SRC="tbullet.gif" NAME="Graphic4" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
Applications of EPSIS</H3>
<P align="justify" class="style1">EPSIS is a research and
development instrumentation platform, comprising hardware and
software tools, that is designed to aid you in your research and
product development. EPSIS frees you from instrumentation
development, allowing you to concentrate on the business end of
things -- the sensing element itself. With EPSIS you can
concentrate on developing your proprietary materials, sensor
configuration and assay protocol.</P>
<div align="justify">
<UL class="style1">
<LI><B>EPSIS Applications in Chemical and
Biological Sensor Development</B> <BR>
<B><FONT COLOR="#00af00">Ø
</FONT>In the development of chemical sensor and biosensor
devices and systems:</B> The high
sensitivity of electroconductive polymer thin films to changes
in redox state, along with the solid state construction and
small device size, make these devices ideally suited for
research and development of chemical and biosensor applications.
The chemical specificity of chemical sensors may be derived form
the use of various indicator agents including: macrocyclic
agents and other inorganic binding compounds, metal occlusions,
and inorganic catalysts. The biological specificity of biosensor
devices may be conferred by the use of immobilized co-factors,
enzymes, antibodies, enzyme-antibody conjugates, stabilized
receptors, and DNA fragments.
</P>
</UL>
<UL>
<LI class="style1">
</UL>
</div>
<UL><LI class="style1"><P align="justify">E<B>PSIS Applications in Gas and Vapor Phase
Sensors</B> <BR><B><FONT COLOR="#00af00">Ø</FONT>
In the development of volatile organic compound
(VOC) gas and vapor sensors and electronic noses:</B> The
ability of electroconductive polymers to reversibly absorb and
desorp organic vapors from within their microstructure with
simultaneous change in electrical conductivity makes these
sensors well suited for the development of VOC probes. EPSIS
boasts a unique two-electrode conductimetric mode suited for the
study of the chemoresistive responses derived from
electroconductive polymer-vapor interactions. Combined with our
<A HREF="picts/gasvapcl.jpg">gas-vapor
sorption cell</A>, EPSIS multiplexes between two sensing
elements located on the same chip.</P>
<LI><P align="justify" class="style1"><B>EPSIS Applications in Polymer Materials
Characterization<BR>
<FONT COLOR="#00af00">Ø</FONT>
In the characterization of novel electroconductive
polymers and other chemically responsive polymers:</B>
EPSIS is conveniently used to study the electrical
properties of various novel electroactive polymer films and
polyelectrolyte gels. Studies such as: the potential dependence
of the electrical conductivity; the ensuing open circuit or
poise potential as a function of impressed polarization
potential; electrical conductivity as a function of counter
anion type and concentration, and dynamic conductivity changes
arising from various environmental factors such as pH,
temperature, etc.
</P>
</UL>
<P ALIGN=LEFT><A HREF="epsis.html#top"><FONT face-arial SIZE=-1>Back
to Index</FONT></A></P> </TD>
</TR>
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</DL>
<H3 ALIGN=LEFT><IMG SRC="tbullet.gif" NAME="Graphic5" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<FONT SIZE=2><FONT FACE="arial">Technical Specifications</FONT></FONT></H3>
<TABLE WIDTH=650 BORDER=0 CELLPADDING=3 CELLSPACING=5>
<TR>
<TD WIDTH=459 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSIS
240<I>II</I></B></FONT></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSISoft
2.0</B></FONT></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><I><B>Technical
Features</B></I></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><I><B>Specifications</B></I></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Chemoresistance
Range</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>10
Ohm to 2 M Ohm</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Chemoresistance
Resolution</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
0.3 %</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Potential
Range</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>-2,048
to +2,048 mV</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Potential
Resolution</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
1 mV</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Ten
(10) User-selectable Current Measuring Scales</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>0.5
to 500 micro A/V</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Response
Time</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>2
micro s</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>A/D
Converter</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>12
bit resolution</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Software
Selectable Gain</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>1,
10, 100, 500</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>A/D
Converter Throughput (speed)</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>45
KHz (22 *s) 2.5 KHz (400 *s)</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Compliance
Voltage</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
12 V at 10 mA</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Maximum
Current</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>10
mA</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Weight,
EPSIS 240U Analog Unit</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>1.6
Kg (2 lbs 4 ozs)</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Dimensions,
EPSIS 240U Analog Unit</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>14
cm W x 4 cm H x 19.5 cm D</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD COLSPAN=2 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSIS
240<I>II</I> CS</B></FONT></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Multimedia
PC</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>200
MHz</B></FONT></FONT></P>
</TD>
</TR>
</TABLE>
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<P ALIGN=CENTER STYLE="margin-bottom: 0in"> <A HREF="epsis.html#top"><FONT SIZE=1 STYLE="font-size: 6pt">Back
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<P><A NAME="methods"></A><IMG SRC="tbullet.gif" NAME="Graphic6" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<B>Principle of Operation</B></P>
<P class="style1">EPSIS is designed to measure the chemoresistance
responses of <A HREF="epmes.html">EPME
devices</A>, <A HREF="babs.html">Bioanalytical
Biosensors</A>, and Electriochemical Biosensors.</P>
<UL class="style1">
<P STYLE="margin-bottom: 0in"><B><FONT COLOR="#00af00">Ø
</FONT></B>Electroactive polymers such as, <I>polypyrrole</I>,
<I>polyaniline</I>, and <I>poly(3-hexylthiophene)</I> display
very dramatic changes in electrical (electronic) conductivity
upon oxidation or reduction. The oxidation/reduction reactions
of these polymers may be driven by an impressed electrode
potential or by the chemical potential energy of a chemical
oxidizing or reducing agent. The resulting electrical
conductivity of these chemically sensitive polymers (under
controlled circumstances) is precisely governed by the state of
charge or extent of oxidation/reduction of the polymer. These
features identify electroconductive polymers as
transducer-active materials well suited to chemical and
biological sensor applications. EPSIS is based on the simple
principle that the amount of current (or charge) traversing a
fixed dimension of electroconductive polymer film may be
modulated by the chemical potential energy (concentration) of an
analyte with which it is in intimate contact and to which it has
been rendered specific. EPSIS uses this chemoresistance
principle and exploits the very large changes in electrical
impedance which accompanies the mediated oxidation/reduction of
electroactive polymers fabricated on interdigitated microsensor
electrodes.<BR>
<BR>
<B><FONT COLOR="#00af00">Ø
</FONT></B>EPSIS uses a patented analytical method which first
evaluates the integrity of the electroconductive polymer device,
initializes it to a user specified extent of charge to establish
a known and reproducible starting electrical conductivity, then
interrogates it with non-pertubating, small amplitude, short
duration pulses to reveal time dependent changes in electronic
conductivity as the device responds to an analyte. Sensor
responses may be kinetic when the rate of change in electrical
conductivity is monitored or equilibrium when the extent of
change in electrical conductivity is monitored. </P>
</UL>
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<H3 class="style1"><A NAME="appnotes"></A><IMG SRC="tbullet.gif" NAME="Graphic7" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
Application Notes</H3>
<P ALIGN=LEFT class="style1">For further
information, request Application Notes:</P>
<BLOCKQUOTE class="style1"><B><FONT COLOR="#00af00">Ø </FONT></B>IME1
- Interdigitated Microsensor Electrodes: Applications and
References.</BLOCKQUOTE>
<BLOCKQUOTE class="style1"><B><FONT COLOR="#00af00">Ø </FONT></B>IME2
- Conductimetric Urea Biosensor Formed From Interdigitated
Microsensor Electrodes</BLOCKQUOTE>
<BLOCKQUOTE class="style1"><B><FONT COLOR="#00af00">Ø </FONT></B>IME3
- Cleaning Procedures</BLOCKQUOTE>
<P class="style1">Electroconductive Polymer
Microsensor Electrode (EPME(TM)) is the trade name for a family
of non-specific sensor devices developed by ABTECH.</P>
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to Index</FONT></A></FONT></FONT></P> </TD>
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