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<TITLE>EPSIS - Electroconductive Polymer Sensor Interrogation System</TITLE>
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<P ALIGN=RIGHT> <B><FONT COLOR="#ffffff">EPSIS
(Electroconductive Polymer Sensor Interrogation System)</FONT></B></P>
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<P><A HREF="http://www.abtechsci.com/gifs/epsis1l.GIF"><IMG SRC="gifs/epsis1s.gif" NAME="Graphic1" ALIGN=BOTTOM WIDTH=110 HEIGHT=134 BORDER=0 ISMAP></A></P>
<P><FONT FACE="Verdana"><FONT SIZE=2><B>Model EPSIS 240 II US</B></FONT></FONT></P>
</TD>
<TD WIDTH=289>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/gifs/epsis2l.GIF"><IMG SRC="gifs/epsis2s.gif" NAME="Graphic2" ALIGN=BOTTOM WIDTH=198 HEIGHT=151 BORDER=0></A></P>
<P ALIGN=CENTER><FONT FACE="Verdana"><FONT SIZE=2><B>Model EPSIS
240 II CS</B></FONT></FONT></P>
</TD>
<TD WIDTH=290 VALIGN=TOP>
<P><A HREF="aboutl.gif"><IMG SRC="gifs/abouts.gif" NAME="Graphic3" ALIGN=BOTTOM WIDTH=165 HEIGHT=130 BORDER=0></A></P>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/gifs/epsscrn3.gif"><B>EPSISoft
Release 2.0</B></A></P>
</TD>
</TR>
</TABLE>
</DL>
<P ALIGN=CENTER><B><I>for </I>B i o s e n s o r A s s a y s</B></P>
<DL>
<DD>
<TABLE WIDTH=886 BORDER=0 CELLPADDING=2 CELLSPACING=0>
<COL WIDTH=206>
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<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/epsis.html#introduction">Introduction
and Background</A></P>
</TD>
<TD WIDTH=173>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/epsis.html#applications">Applications
of EPSIS</A></P>
</TD>
<TD WIDTH=184>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/epsis.html#specifications">Technical
Specifications</A></P>
</TD>
<TD WIDTH=82>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/epsis.html#methods">Principle</A></P>
</TD>
<TD WIDTH=138>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/epsis.html#appnotes">Application
Notes</A></P>
</TD>
<TD WIDTH=79>
<P ALIGN=CENTER><A HREF="http://www.abtechsci.com/pricelist.html">Price
List</A></P>
</TD>
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<P><IMG SRC="tbullet.gif" NAME="Graphic10" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<B>Introduction and Background</B></P>
<BLOCKQUOTE><FONT FACE="Verdana"><FONT SIZE=1>The EPSIS 240II now
boasts a new hardware configuration for software selectable two
electrode and three electrode modes of sensor interrogation. This
is a key and important development. With the two electrode mode,
the user may now reliably and conveniently interrogate conductive
polymer gas and vapor phase analytes -- useful in the development
of electronic noses and VOC sensors - without resorting to
previous electrode patch-ins. EPSIS continues, in its
three-electrode mode, to offer its innovative electroconductive
polymer sensor interrogation configuration for the development of
conductimetric chemical sensors and biosensors.</FONT></FONT></BLOCKQUOTE>
<BLOCKQUOTE><FONT FACE="Verdana"><FONT SIZE=1>EPSIS is the first
of its kind sensor interrogation system designed specifically for
research and applications-specific product development of
chemical and biological sensors based on electroconductive
polymer sensor technology. EPSIS is based on a patented
analytical method that combines potentiometric, potentiostatic,
and superior pulsed DC chronocoulometric capabilities in one
unit. These electrochemical capabilities are sequentially
combined to provide a powerful and versatile detection and
measurement scheme that is unique to electroconductive polymer
transducers. The result is a conductimetric response that
detects, measures, and reports changes in electrical conductivity
as electroconductive transducers respond to specific analytes to
which they have been rendered chemically or biologically
specific.</FONT></FONT></BLOCKQUOTE>
<P ALIGN=LEFT><A HREF="http://www.abtechsci.com/epsis.html#top"><FONT SIZE=1 STYLE="font-size: 6pt">Back
to Index</FONT></A></P>
<HR>
<H3 ALIGN=LEFT><IMG SRC="tbullet.gif" NAME="Graphic4" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<FONT SIZE=2><FONT FACE="Verdana">Applications of EPSIS</FONT></FONT></H3>
<P><FONT FACE="Verdana"><FONT SIZE=1>EPSIS is a research and
development instrumentation platform, comprising hardware and
software tools, that is designed to aid you in your research and
product development. EPSIS frees you from instrumentation
development, allowing you to concentrate on the business end of
things -- the sensing element itself. With EPSIS you can
concentrate on developing your proprietary materials, sensor
configuration and assay protocol.</FONT></FONT></P>
<UL>
<LI><P><B><FONT SIZE=1>EPSIS Applications in Chemical and
Biological Sensor Development</FONT></B> <BR><B><FONT SIZE=1><FONT COLOR="#00af00">Ø
</FONT>In the development of chemical sensor and biosensor
devices and systems:</FONT></B> <FONT SIZE=1>The high
sensitivity of electroconductive polymer thin films to changes
in redox state, along with the solid state construction and
small device size, make these devices ideally suited for
research and development of chemical and biosensor applications.
The chemical specificity of chemical sensors may be derived form
the use of various indicator agents including: macrocyclic
agents and other inorganic binding compounds, metal occlusions,
and inorganic catalysts. The biological specificity of biosensor
devices may be conferred by the use of immobilized co-factors,
enzymes, antibodies, enzyme-antibody conjugates, stabilized
receptors, and DNA fragments.</FONT>
</P>
</UL>
<UL>
<LI><P><FONT SIZE=1>E<B>PSIS Applications in Gas and Vapor Phase
Sensors</B></FONT> <BR><B><FONT SIZE=1><FONT COLOR="#00af00">Ø</FONT></FONT>
<FONT SIZE=1>In the development of volatile organic compound
(VOC) gas and vapor sensors and electronic noses:</FONT></B> <FONT SIZE=1>The
ability of electroconductive polymers to reversibly absorb and
desorp organic vapors from within their microstructure with
simultaneous change in electrical conductivity makes these
sensors well suited for the development of VOC probes. EPSIS
boasts a unique two-electrode conductimetric mode suited for the
study of the chemoresistive responses derived from
electroconductive polymer-vapor interactions. Combined with our
<A HREF="http://www.abtechsci.com/picts/gasvapcl.jpg">gas-vapor
sorption cell</A>, EPSIS multiplexes between two sensing
elements located on the same chip.</FONT></P>
<LI><P><B><FONT SIZE=1>EPSIS Applications in Polymer Materials
Characterization<BR><FONT COLOR="#00af00">Ø</FONT></FONT>
<FONT SIZE=1>In the characterization of novel electroconductive
polymers and other chemically responsive polymers:</FONT></B>
<FONT SIZE=1>EPSIS is conveniently used to study the electrical
properties of various novel electroactive polymer films and
polyelectrolyte gels. Studies such as: the potential dependence
of the electrical conductivity; the ensuing open circuit or
poise potential as a function of impressed polarization
potential; electrical conductivity as a function of counter
anion type and concentration, and dynamic conductivity changes
arising from various environmental factors such as pH,
temperature, etc.</FONT>
</P>
</UL>
<P ALIGN=LEFT><A HREF="http://www.abtechsci.com/epsis.html#top"><FONT SIZE=1>Back
to Index</FONT></A></P>
</TD>
</TR>
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<HR WIDTH=143165425 ALIGN=RIGHT>
</DL>
<H3 ALIGN=LEFT><IMG SRC="tbullet.gif" NAME="Graphic5" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<FONT SIZE=2><FONT FACE="Verdana">Technical Specifications</FONT></FONT></H3>
<CENTER>
<TABLE WIDTH=88% BORDER=0 CELLPADDING=3 CELLSPACING=5>
<TR>
<TD WIDTH=459 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSIS
240<I>II</I></B></FONT></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSISoft
2.0</B></FONT></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><I><B>Technical
Features</B></I></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><I><B>Specifications</B></I></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Chemoresistance
Range</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>10
Ohm to 2 M Ohm</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Chemoresistance
Resolution</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
0.3 %</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Potential
Range</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>-2,048
to +2,048 mV</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Potential
Resolution</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
1 mV</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Ten
(10) User-selectable Current Measuring Scales</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>0.5
to 500 micro A/V</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Response
Time</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>2
micro s</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>A/D
Converter</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>12
bit resolution</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Software
Selectable Gain</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>1,
10, 100, 500</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>A/D
Converter Throughput (speed)</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>45
KHz (22 *s) 2.5 KHz (400 *s)</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Compliance
Voltage</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>+/-
12 V at 10 mA</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Maximum
Current</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>10
mA</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Weight,
EPSIS 240U Analog Unit</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>1.6
Kg (2 lbs 4 ozs)</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Dimensions,
EPSIS 240U Analog Unit</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>14
cm W x 4 cm H x 19.5 cm D</B></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD COLSPAN=2 BGCOLOR="#cccccc">
<P ALIGN=CENTER><FONT COLOR="#af0000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>EPSIS
240<I>II</I> CS</B></FONT></FONT></FONT></P>
</TD>
</TR>
<TR>
<TD WIDTH=459 BGCOLOR="#d1dbe9">
<P><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>Multimedia
PC</B></FONT></FONT></P>
</TD>
<TD WIDTH=208 BGCOLOR="#ebd9cf">
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt"><B>200
MHz</B></FONT></FONT></P>
</TD>
</TR>
</TABLE>
</CENTER>
<P ALIGN=CENTER STYLE="margin-bottom: 0in"> <A HREF="http://www.abtechsci.com/epsis.html#top"><FONT SIZE=1 STYLE="font-size: 6pt">Back
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<P><A NAME="methods"></A><IMG SRC="tbullet.gif" NAME="Graphic6" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<B>Principle of Operation</B></P>
<P><FONT SIZE=1>EPSIS is designed to measure the chemoresistance
responses of <A HREF="http://www.abtechsci.com/epmes.html">EPME
devices</A>, <A HREF="http://www.abtechsci.com/babs.html">Bioanalytical
Biosensors</A>, and Electriochemical Biosensors.</FONT></P>
<UL>
<P STYLE="margin-bottom: 0in"><FONT SIZE=1><FONT FACE="Verdana"><B><FONT COLOR="#00af00">Ø
</FONT></B>Electroactive polymers such as, <I>polypyrrole</I>,
<I>polyaniline</I>, and <I>poly(3-hexylthiophene)</I> display
very dramatic changes in electrical (electronic) conductivity
upon oxidation or reduction. The oxidation/reduction reactions
of these polymers may be driven by an impressed electrode
potential or by the chemical potential energy of a chemical
oxidizing or reducing agent. The resulting electrical
conductivity of these chemically sensitive polymers (under
controlled circumstances) is precisely governed by the state of
charge or extent of oxidation/reduction of the polymer. These
features identify electroconductive polymers as
transducer-active materials well suited to chemical and
biological sensor applications. EPSIS is based on the simple
principle that the amount of current (or charge) traversing a
fixed dimension of electroconductive polymer film may be
modulated by the chemical potential energy (concentration) of an
analyte with which it is in intimate contact and to which it has
been rendered specific. EPSIS uses this chemoresistance
principle and exploits the very large changes in electrical
impedance which accompanies the mediated oxidation/reduction of
electroactive polymers fabricated on interdigitated microsensor
electrodes.<BR><BR></FONT><B><FONT COLOR="#00af00">Ø
</FONT></B>EPSIS uses a patented analytical method which first
evaluates the integrity of the electroconductive polymer device,
initializes it to a user specified extent of charge to establish
a known and reproducible starting electrical conductivity, then
interrogates it with non-pertubating, small amplitude, short
duration pulses to reveal time dependent changes in electronic
conductivity as the device responds to an analyte. Sensor
responses may be kinetic when the rate of change in electrical
conductivity is monitored or equilibrium when the extent of
change in electrical conductivity is monitored.</FONT>
</P>
</UL>
<P ALIGN=LEFT><A HREF="http://www.abtechsci.com/epsis.html#top"><FONT SIZE=1>Back
to Index</FONT></A></P>
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<H3><A NAME="appnotes"></A><IMG SRC="tbullet.gif" NAME="Graphic7" ALIGN=BOTTOM WIDTH=12 HEIGHT=12 BORDER=0>
<FONT SIZE=2><FONT FACE="Verdana">Application Notes</FONT></FONT></H3>
<P ALIGN=LEFT><FONT FACE="Verdana"><FONT SIZE=1>For further
information, request Application Notes:</FONT></FONT></P>
<BLOCKQUOTE><FONT SIZE=1><B><FONT COLOR="#00af00">Ø </FONT></B>IME1
- Interdigitated Microsensor Electrodes: Applications and
References.</FONT></BLOCKQUOTE>
<BLOCKQUOTE><FONT SIZE=1><B><FONT COLOR="#00af00">Ø </FONT></B>IME2
- Conductimetric Urea Biosensor Formed From Interdigitated
Microsensor Electrodes</FONT></BLOCKQUOTE>
<BLOCKQUOTE><FONT SIZE=1><B><FONT COLOR="#00af00">Ø </FONT></B>IME3
- Cleaning Procedures</FONT></BLOCKQUOTE>
<P><FONT FACE="Verdana"><FONT SIZE=1>Electroconductive Polymer
Microsensor Electrode (EPME(TM)) is the trade name for a family
of non-specific sensor devices developed by ABTECH.</FONT></FONT></P>
<P><A HREF="http://www.abtechsci.com/epsis.html#top"><FONT SIZE=1>Back
to Index</FONT></A></P>
<HR>
<P ALIGN=CENTER><FONT FACE="Verdana, sans-serif"><FONT SIZE=1 STYLE="font-size: 8pt">Last
Revision 11/05/2004<BR>© 2004 ABTECH Scientific,
Inc.<BR></FONT><FONT SIZE=2 STYLE="font-size: 9pt"><BR></FONT></FONT><FONT SIZE=1><FONT FACE="Verdana, Arial"><B>Contact:
Ann M. Wilson, </B>Manager, <BR>Applications Development ABTECH
Scientific, Inc.<BR>911 East Leigh Street G24, Richmond, Virginia
23219<BR>Telephone Number: +1-804-783-7829 Fax Number:
+1-804-783-7830<BR>e-mail: <A HREF="[email protected]">[email protected]</A></FONT></FONT></P>
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