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<P ALIGN=RIGHT><FONT SIZE=1><FONT FACE="Verdana"><FONT COLOR="#808000">ABTECH-e-Acta</FONT><BR><STRONG>May
2005</STRONG></FONT></FONT></P>
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<P><A HREF="http://www.abtechsci.com/"><IMG SRC="Logoscn2_sm.gif" NAME="Graphic1" ALT="Logoscn2_sm.gif (1755 bytes)" ALIGN=BOTTOM WIDTH=88 HEIGHT=49 BORDER=0></A></P>
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<P><FONT SIZE=1><FONT FACE="Verdana">This is our quick and easy
way to let you know what we're up to and how things are going in
the biochip industry. To unsubscribe, there's a link at the end of
this email. If you have feedback, please <A HREF="mailto:[email protected]">email</A>
us your comments.</FONT></FONT>
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<P ALIGN=CENTER><STRONG><FONT COLOR="#008000">Conferences</FONT></STRONG></P>
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<P><FONT COLOR="#ff0000"><FONT FACE="Verdana Ref">News for Users:</FONT></FONT></P>
<H3><FONT FACE="Verdana"><FONT SIZE=2>Electrochemical
Cell-on-a-Chip (ECC)</FONT></FONT></H3>
<BLOCKQUOTE STYLE="margin-right: 1.18in; text-decoration: none"><FONT COLOR="#000000"><FONT FACE="Verdana"><FONT SIZE=1>The
Electrochemical Cell-on-a-Chip (ECC) is a microlithographically
fabricated transducer array that is well suited for chemical and
biosensor research and product development. It is available in two
characteristic ABTECH microelectrode formats: i) the
interdigitated microsensor electrode (IME) format of a pair of
fingered working electrodes in circular aspect, and ii) the
microdisc electrode array (MDEA) format of many conducting discs
set beneath tiny openings in an insulating layer of silicon
nitride. </FONT></FONT></FONT>
</BLOCKQUOTE>
<BLOCKQUOTE STYLE="margin-right: 1.18in"><FONT FACE="Verdana"><FONT SIZE=1>Both
the ECC IME and ECC MDEA are formed from patterned conductors
(Gold, Platinum and ITO) on an insulating substrate (borosilicate
glass) chip. The electrode buses are passivated with an insulating
layer (0.5<FONT FACE="Symbol, serif">m</FONT>) of silicon nitride
(<FONT FACE="Verdana, sans-serif">Si<SUB>3</SUB>N<SUB>4</SUB></FONT>).
<FONT FACE="Verdana, sans-serif">The ECC IMEs are 1.0 cm x 2.0 cm
x 0.05 cm chips designed with a total of five (5) interdigitated
fingers on each bus; ten fingers altogether. The interdigitated
bands and spacings of ECC IME chips are available in 05, 10, 15,
and 20 microns wide. The length of the fingers vary, depending on
the width of the fingers and spaces. The ECC IME XX05 chips are
available in gold (Au), platinum (Pt). and indium tin oxide (ITO).
Each IME array is partnered with its own large area counter
electrode and both IME arrays share a common reference electrode.
The ECC IME XX05 chip therefore has a total of seven (7)
electrodes. The ECC MDEAs are 0.2 cm x 0.4 cm x 0.05 cm chips
designed with two (2) independently addressable microdisc array
electrodes. Each microdisc array comprises discs that are 50
micron in diameter. A total of 37 such discs are formed through an
<FONT FACE="Verdana">insulating layer (0.5<FONT FACE="Symbol, serif">m</FONT>)
of silicon nitride (<FONT FACE="Verdana, sans-serif">Si<SUB>3</SUB>N<SUB>4</SUB></FONT>)</FONT>;
hence ECC MDEA 5037. The ECC MDEA 5037 is available in gold (Au),
platinum (Pt), and indium tin oxide (ITO). Each microdisc array is
partnered with its own large area counter electrode and both
microdisc arrays share a common reference electrode. The ECC MDEA
5037 therefore has a total of five (5) electrodes.</FONT></FONT></FONT></BLOCKQUOTE>
<P STYLE="margin-left: 0.19in"><A HREF="http://www.abtechsci.com/eccime.html"><FONT SIZE=1><FONT FACE="Verdana">More-></FONT></FONT></A></P>
<H3><FONT FACE="Verdana"><FONT SIZE=2>Microfabricated Chips Enable
Advanced Biosensor and Biochip Research</FONT></FONT></H3>
<P><FONT SIZE=1><FONT FACE="Verdana">ABTECH's line of
microlithographically fabricated interdigitated microsensor
electrodes, microband electrodes, and micodisc electrode arrays
are well suited to the development of impedimetric, amperometric
and voltametric chemical and biological sensors. Look for new
polished and metallized (Au or Pt) 3” x 1”
borosilicate glass substrates for DNA Microarrays – Summer
2005 <A HREF="http://www.abtechsci.com/labproducts.html">More-></A></FONT></FONT></P>
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<P><A HREF="http://www.chemistry.org/portal/a/c/s/1/acsdisplay.html?DOC=education\professional\scpr18.html"><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana, sans-serif"><FONT COLOR="#000000">Introduction
to Polymers in Medicine</FONT></FONT></FONT></SPAN></A></P>
<P STYLE="font-weight: medium"><FONT COLOR="#000000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1>The
School of Engineering<BR>Virginia Commonwealth
University<BR>Richmond, VA, USA </FONT></FONT></FONT>
</P>
<P STYLE="font-weight: medium"><FONT COLOR="#000000"><FONT FACE="Verdana, sans-serif"><FONT SIZE=1>Jun
7-10, 2005 </FONT></FONT></FONT>
</P>
<P><FONT SIZE=1><FONT FACE="Verdana, sans-serif"><FONT COLOR="#000000">American
Chemical Society<BR>To Register: <A HREF="http://acswebapplications.acs.org/PortalTools/Login.cfm?view=oscr&uid=&acsmemberid=">More-></A></FONT></FONT></FONT></P>
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<P><A HREF="http://conductivepolymers.com/seminar.htm"><SPAN STYLE="background: transparent"><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana"><FONT COLOR="#000000">XII<SUP>th</SUP>
International Seminar on the Technology of Inherently Conductive
Polymers</FONT></FONT></FONT></SPAN></SPAN></A></P>
<P><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana, sans-serif"><A HREF="http://www.fairmont.com/copleyplaza/http://www.fairmont.com/copleyplaza/"><SPAN STYLE="background: transparent"><SPAN STYLE="text-decoration: none"><FONT COLOR="#000000">The
Fairmont Copley Plaza</FONT></SPAN></SPAN></A><SPAN STYLE="background: transparent"><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana"><FONT COLOR="#000000"><BR><FONT FACE="Verdana, sans-serif">138
St. James Avenue, <BR>Boston, MA 02116 USA</FONT></FONT></FONT></FONT></SPAN></SPAN></FONT></FONT></SPAN></P>
<P STYLE="font-weight: medium; text-decoration: none"><FONT COLOR="#000000"><FONT FACE="Verdana"><FONT SIZE=1><SPAN STYLE="background: transparent">October
3-5, 2005</SPAN></FONT></FONT></FONT></P>
<P><SPAN STYLE="background: transparent"><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana"><FONT COLOR="#000000"><FONT SIZE=1>Advanced
Polymer Courses</FONT><BR><FONT SIZE=1>To Register: </FONT><A HREF="http://conductivepolymers.com/semreg.htm"><SPAN STYLE="text-decoration: none"><FONT SIZE=1>More-></FONT></SPAN></A></FONT></FONT></FONT></SPAN></SPAN></P>
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<TD ROWSPAN=2 WIDTH=21%>
<P><A HREF="http://www.abtechsci.com/files.html"><SPAN STYLE="background: transparent"><SPAN STYLE="text-decoration: none"><FONT SIZE=1><FONT FACE="Verdana"><FONT COLOR="#000000">Biomedical
Diagnostics using Electroconductive Bio-smart Thin Films</FONT></FONT></FONT></SPAN></SPAN></A></P>
<P><FONT SIZE=2><FONT FACE="Verdana"><STRONG><FONT SIZE=1>Anthony
Guiseppi-Elie, Sc.D.</FONT></STRONG><BR><FONT SIZE=1>President and
Scientific Director</FONT><BR><FONT SIZE=1>ABTECH Scientific, Inc.</FONT></FONT></FONT></P>
</TD>
<TD COLSPAN=8 WIDTH=77%>
<P ALIGN=CENTER><FONT SIZE=1><FONT FACE="Verdana">Electrochemical
Cell-on-a-Chip <A HREF="http://www.abtechsci.com/eccime.html"><SPAN STYLE="text-decoration: none">More-></SPAN></A></FONT></FONT></P>
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<TD COLSPAN=3 WIDTH=18%>
<P ALIGN=CENTER><A HREF="gifs/eccxx05digits.JPG" NAME="eccxx05digits"><FONT COLOR="#000080"><IMG SRC="gifs/eccxx05digits.JPG" NAME="Graphic2" ALT="Electrochemical Cell-on-a-Chip Array" ALIGN=RIGHT WIDTH=112 HEIGHT=100 BORDER=1><BR CLEAR=RIGHT></FONT></A><BR>
</P>
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<TD WIDTH=12%>
<A HREF="picts/eccime1.JPG"><FONT COLOR="#000080"><IMG SRC="picts/eccime1.JPG" NAME="ECC IME XX05 pic" ALT="Electrochemical Cell-on-a-Chip Array" ALIGN=LEFT WIDTH=138 HEIGHT=100 BORDER=1><BR CLEAR=LEFT></FONT></A></TD>
<TD WIDTH=12%>
<A HREF="gifs/eccxx05chip.JPG"><FONT COLOR="#000080"><IMG SRC="gifs/eccxx05chip.JPG" NAME="ECC IME XX05 Chip" ALT="ECC IME XX05 Chip" ALIGN=LEFT WIDTH=185 HEIGHT=97 BORDER=1><BR CLEAR=LEFT></FONT></A></TD>
<TD WIDTH=12%>
<A HREF="gifs/eccxx05cell.JPG" NAME="ECC IME XX05 Cell"><FONT COLOR="#000080"><IMG SRC="gifs/eccxx05cell.JPG" NAME="ECC IME XX05 Cell" ALT="ECC IME XX05 Cell" ALIGN=RIGHT WIDTH=133 HEIGHT=101 BORDER=1><BR CLEAR=RIGHT></FONT></A></TD>
<TD WIDTH=12%>
<A HREF="picts/ecccell1.jpg"><FONT COLOR="#000080"><IMG SRC="picts/ecccell1.jpg" NAME="ECC IME XX05 cell" ALT="Electrochemical Cell-on-a-Chip Array" ALIGN=LEFT WIDTH=139 HEIGHT=100 BORDER=1><BR CLEAR=LEFT></FONT></A></TD>
<TD WIDTH=13%>
<A HREF="gifs/ECCMDEA5037_chip.bmp" NAME="ECC MDEA 5037 Cell"><FONT COLOR="#000080"><IMG SRC="gifs/ECCMDEA5037_cell.bmp" NAME="ECC MDEA 5037 Chip" ALT="ECC MDEA 5037 Chip" ALIGN=LEFT WIDTH=93 HEIGHT=96 BORDER=1><BR CLEAR=LEFT></FONT></A></TD>
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